Two novel Pd thiosemicarbazone complexes as efficient and selective antitumoral drugs-Reference-Cited by-同舟云学术

Two novel Pd thiosemicarbazone complexes as efficient and selective antitumoral drugs

Published:2023 Issue:7 Volume:10 Page:1986-1998
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Hidalgo Tania¹^ORCID,Fabra David²^ORCID,Allende Raul²,Matesanz Ana I.²^ORCID,Horcajada Patricia¹^ORCID,Biver Tarita³^ORCID,Quiroga Adoracion G.²^ORCID

Affiliation:

1. Advanced Porous Materials Unit (APMU), IMDEA Energy Institute, Av. Ramon de la Sagra 3, 28935 Móstoles-Madrid, Spain

2. Department of Inorganic Chemistry Universidad Autonoma de Madrid, 28049 Madrid, Spain

3. Univ Pisa, Dept Chem & Ind Chem DCCI, Via Moruzzi 13, I-56124 Pisa, Italy

Abstract

Two Palladium complexes are presented as a promising alternative to platinum drugs disadvantages, controlling the speciation and limiting toxicity. Their interaction vs. biological targets and their efficiency are demonstrated, being more specific than the benchmark cisplatin drug.

Funder

European Cooperation in Science and Technology

European Regional Development Fund

Horizon 2020 Framework Programme

Ministerio de Ciencia, Innovación y Universidades

Secretaría de Estado de Investigación, Desarrollo e Innovación

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QI/D2QI02424A