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Examining platelet adhesion via Stokes flow simulations and microfluidic experiments

Published:2015 Issue:2 Volume:11 Page:355-367
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Fitzgibbon Sean¹²³,Cowman Jonathan⁴⁵⁶,Ricco Antonio J.⁷⁸⁹,Kenny Dermot⁷⁵⁶,Shaqfeh Eric S. G.¹¹⁰¹¹²³

Affiliation:

1. Chemical Engineering

2. Stanford University

3. Stanford, USA

4. Biomedical Diagnostic Institute

5. Royal College of Surgeons in Ireland

6. Dublin 2, Ireland

7. Biomedical Diagnostics Institute

8. Dublin City University

9. Dublin 9, Ireland

10. Mechanical Engineering

11. Institute for Computational and Mathematical Engineering

Abstract

While critically important, the platelet function at the high shear rates typical of the microcirculation is relatively poorly understood.

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/SM/C4SM01450B

Reference43 articles.

1. Platelets in hemostasis and thrombosis: role of integrins and their ligands

2. Anemia-induced increase in the bleeding time:implications for treatment of nonsurgical blood loss

3. Shear-induced particle migration and margination in a cellular suspension

4. A3 Domain Is Essential for Interaction of von Willebrand Factor with Collagen Type III

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2. A Multiscale Model for Shear-Mediated Platelet Adhesion Dynamics: Correlating In Silico with In Vitro Results;Annals of Biomedical Engineering;2023-04-05

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