Exploring the relationship between structure and activity in BODIPYs designed for antimicrobial phototherapy-Reference-Cited by-同舟云学术

Exploring the relationship between structure and activity in BODIPYs designed for antimicrobial phototherapy

Published:2020 Issue:13 Volume:18 Page:2416-2431
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Hohlfeld Benjamin F.¹²³⁴⁵^ORCID,Gitter Burkhard⁶⁷⁴,Flanagan Keith J.⁸⁹¹⁰¹¹¹²^ORCID,Kingsbury Christopher J.⁸⁹¹⁰¹¹¹²^ORCID,Kulak Nora⁵²³⁴¹³^ORCID,Senge Mathias O.⁸⁹¹⁰¹¹¹²^ORCID,Wiehe Arno¹²³⁴⁶^ORCID

Affiliation:

1. Institut für Chemie u. Biochemie

2. Freie Universität Berlin

3. 14195 Berlin

4. Germany

5. Institut für Chemie und Biochemie

6. biolitec research GmbH

7. 07745 Jena

8. Medicinal Chemistry

9. Trinity Translational Medicine Institute

10. Trinity Centre for Health Sciences

11. Trinity College Dublin

12. The University of Dublin

13. Institut für Chemie

Abstract

A series of BODIPYs were evaluated for their phototoxic activity against Gram-positive S. aureus and Gram-negative P. aeruginosa. Specifically, carbohydrate/dibromosubstituted BODIPYs showed a highly effective inactivation of S. aureus.

Funder

H2020 Marie Skłodowska-Curie Actions

Science Foundation Ireland

Bundesministerium für Bildung und Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00188K

Reference94 articles.

1. Antimicrobial resistance: global report on surveillance 2014, https://www.who.int/drugresistance/documents/surveillancereport/en