Bromo- and glycosyl-substituted BODIPYs for application in photodynamic therapy and imaging-Reference-Cited by-同舟云学术

Bromo- and glycosyl-substituted BODIPYs for application in photodynamic therapy and imaging

Published:2023 Issue:15 Volume:21 Page:3105-3120
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Hohlfeld Benjamin F.¹²,Steen Dorika²,Wieland Gerhard D.²^ORCID,Achazi Katharina¹,Kulak Nora¹³^ORCID,Haag Rainer¹,Wiehe Arno¹²^ORCID

Affiliation:

1. Institut für Chemie u. Biochemie, Freie Universität Berlin, Takustr. 3, 14195 Berlin, Germany

2. Biolitec research GmbH, Otto-Schott-Str. 15, 07745 Jena, Germany

3. Institut für Chemie, Otto-von-Guericke-Universität Magdeburg, Universitätsplatz 2, 39106 Magdeburg, Germany

Abstract

Structurally diverse BODIPYs were evaluated for their phototoxic activity against four cancer cell lines in a PDT optimization approach. In particular, glycosylated dibromo-BODIPYs showed a high phototoxic effect, as well as pronounced cellular uptake.

Funder

Bundesministerium für Bildung und Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D2OB02174A

Reference121 articles.

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