An ultrasensitive “turn-off” SERS sensor for quantitatively detecting heparin based on 4-mercaptobenzoic acid functionalized gold nanoparticles
Author:
Affiliation:
1. Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education
2. School of Chemistry and Environment
3. Beihang University
4. Beijing 100191
5. China
6. School of Physics and Nuclear Energy Engineering
Abstract
We develop an ultrasensitive “turn off” Surface Enhanced Raman Spectroscopy (SERS) sensor for the detection of heparin based on the anti-aggregation of 4-mercaptobenzoic acid stabilized gold nanoparticles.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Engineering,General Chemical Engineering,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/AY/C7AY00494J
Reference35 articles.
1. Heparin and heparan sulfate: structure and function
2. Reversible Electrochemical Detection of Nonelectroactive Polyions
3. Order out of complexity – protein structures that interact with heparin
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