Order out of complexity – protein structures that interact with heparin

Author:

Mulloy Barbara,Linhardt Robert J

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference45 articles.

1. Heparin and heparan sulfate: biosynthesis, structure and function;Sasisekharan;Curr Opin Chem Biol,2000

2. Heparan sulfate: decoding a dynamic multifunctional cell regulator;Turnbull;Trends Cell Biol,2001

3. Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme;Forsberg;Nature,1999

4. Heparin is essential for the storage of specific granule proteases in mast cells;Humphries;Nature,1999

5. Capila I, Linhardt RJ: Heparin-protein interactions. Angew Chem Int Ed Engl 2001, in press. An up-to-date and thorough review of interactions between heparin and proteins, with useful introductory material on the structures of heparin and HS. Kinetics, as well as structures, of heparin–protein interactions are dealt with and set in physiological and pharmaceutical contexts.

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