Autocatalytic photoinduced oxidative dehydrogenation of pyrido[2,3-<i>d</i>]pyrimidin-7(8<i>H</i>)-ones: synthesis of C5–C6 unsaturated systems with concomitant formation of a long-lived radical-Reference-Cited by-同舟云学术

Autocatalytic photoinduced oxidative dehydrogenation of pyrido[2,3-d]pyrimidin-7(8H)-ones: synthesis of C5–C6 unsaturated systems with concomitant formation of a long-lived radical

Published:2024 Issue:1 Volume:11 Page:27-36
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

de Rocafiguera Claudi¹^ORCID,Lloveras Vega²^ORCID,Vidal-Gancedo José²^ORCID,Teixidó Jordi¹^ORCID,Estrada-Tejedor Roger¹,Borrell José I.¹^ORCID,Puig de la Bellacasa Raimon¹^ORCID

Affiliation:

1. Grup de Química Farmacèutica, Institut Químic de Sarrià, Universitat Ramon Llull, Via Augusta, 390, E-08017 Barcelona, Spain

2. Institut de Ciència de Materials de Barcelona (ICMAB-CSIC) and CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, Campus UAB, E-08193 Bellaterra, Spain

Abstract

5,6-Dihydropyrido[2,3-d]pyrimidin-7(8H)-ones are readily accessed by a variety of methods and are a good scaffold for the development of biologically active compounds.

Funder

Ministerio de Ciencia, Innovación y Universidades

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D3QO01358H

Reference18 articles.

1. 4-Amino-2-arylamino-6-(2,6-dichlorophenyl)-pyrido[2,3-d]pyrimidin-7-(8H)-ones as BCR kinase inhibitors for B lymphoid malignancies

2. Overcoming Paradoxical Kinase Priming by a Novel MNK1 Inhibitor

3. Expanding the Diversity at the C-4 Position of Pyrido[2,3-d]pyrimidin-7(8H)-ones to Achieve Biological Activity against ZAP-70

4. Synthesis of 2-arylamino substituted 5,6-dihydropyrido[2,3-d]pyrimidine-7(8H)-ones from arylguanidines

5. A captured room temperature stable Wheland intermediate as a key structure for the orthogonal decoration of 4-amino-pyrido[2,3-d]pyrimidin-7(8H)-ones