Selective covalent capture of a DNA sequence corresponding to a cancer-driving C>G mutation in theKRASgene by a chemically reactive probe: optimizing a cross-linking reaction with non-canonical duplex structures-Reference-Cited by-同舟云学术

Selective covalent capture of a DNA sequence corresponding to a cancer-driving C>G mutation in theKRASgene by a chemically reactive probe: optimizing a cross-linking reaction with non-canonical duplex structures

Published:2019 Issue:56 Volume:9 Page:32804-32810
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Guo Xu¹²³⁴,Nejad Maryam Imani¹²³⁴,Gu Li-Qun⁵⁶²³⁴^ORCID,Gates Kent S.¹²³⁴⁷^ORCID

Affiliation:

1. Department of Chemistry

2. University of Missouri

3. Columbia

4. USA

5. Department of Bioengineering

6. Dalton Cardiovascular Research Center

7. Department of Biochemistry

Abstract

A covalent cross-linking reaction used for selective capture of a disease-relevant DNA sequence.

Funder

National Human Genome Research Institute

National Institute of General Medical Sciences

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA08009K

Reference51 articles.

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2. A Selective Turn-On Fluorescent Sensor for Sulfur Mustard Simulants

3. Chemical tags: inspiration for advanced imaging techniques

4. Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

5. Protein Organic Chemistry and Applications for Labeling and Engineering in Live-Cell Systems

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