Synthesis of DNA Duplexes Containing Site-Specific Interstrand Cross-Links via Sequential Reductive Amination Reactions Involving Diamine Linkers and Abasic Sites on Complementary Oligodeoxynucleotides
Author:
Affiliation:
1. Department of Chemistry, University of Missouri, 125 Chemistry Building, Columbia, Missouri 65211, United States
2. Department of Biochemistry, University of Missouri, 125 Chemistry Building, Columbia, Missouri 65211, United States
Funder
National Institute of Environmental Health Sciences
Division of Chemistry
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.1c00293
Reference85 articles.
1. The evolving role of DNA inter-strand crosslinks in chemotherapy
2. A New Cross-Link for an Old Cross-Linking Drug: The Nitrogen Mustard Anticancer Agent Mechlorethamine Generates Cross-Links Derived from Abasic Sites in Addition to the Expected Drug-Bridged Cross-Links
3. Formation and repair of unavoidable, endogenous interstrand cross-links in cellular DNA
4. What is the DNA repair defect underlying Fanconi anemia?
5. DNA Damage and Associated DNA Repair Defects in Disease and Premature Aging
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