Identification of 4-isopropyl–thiotropolone as a novel anti-microbial: regioselective synthesis, NMR characterization, and biological evaluation-Reference-Cited by-同舟云学术

Identification of 4-isopropyl–thiotropolone as a novel anti-microbial: regioselective synthesis, NMR characterization, and biological evaluation

Author:

Elagawany Mohamed¹²³⁴⁵,Hegazy Lamees¹²³⁴,Cao Feng⁶⁷³⁴,Donlin Maureen J.⁸²³⁴,Rath Nigam⁹¹⁰¹¹³⁴,Tavis John¹²¹³²³⁴,Elgendy Bahaa¹²³⁴¹⁴^ORCID

Affiliation:

1. Departments of Pharmacology and Physiology

2. Saint Louis University School of Medicine

3. St. Louis

4. USA

5. Department of Pharmaceutical Chemistry

6. John Cochran Division

7. Department of Veteran's Affairs Medical Center

8. Edward A. Doisy Department of Biochemistry and Molecular Biology

9. Department of Chemistry and Biochemistry

10. Center for Nanoscience

11. University of Missouri – St. Louis

12. Department of Molecular Microbiology and Immunology

13. The Saint Louis University Liver Center

14. Chemistry Department

Abstract

4-Isopropyl–thiotropolone was identified as a novel anti-microbial agent with good therapeutic index and ADME properties.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

Reference40 articles.

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