Graphene oxide aptasensor droplet assay for detection of metabolites secreted by single cells applied to synthetic biology

Author:

Zheng Dan1,Zhang Jingyun1,Jiang Wenxin2,Xu Ying2ORCID,Meng Haixu2,Poh Chueh Loo1,Chen Chia-Hung23ORCID

Affiliation:

1. Department of Biomedical Engineering, National University of Singapore, 4 Engineering Drive 3, 117583, Singapore

2. Department of Biomedical Engineering, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon Tong, Hong Kong, China

3. City University of Hong Kong Shenzhen Research Institute, Shenzhen Virtual University Park, Shenzhen, China

Abstract

A modifiable droplet graphene oxide (GO) aptasensor has been developed for low-background detection of various target compounds with enhanced signal-to-noise ratios for synthetic biology applications.

Funder

National Research Foundation Singapore

Health and Medical Research Fund

National Natural Science Foundation of China

City University of Hong Kong

Innovation and Technology Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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