Alkyl chain substituted 1,9-pyrazoloanthrones exhibit prominent inhibitory effect on c-Jun N-terminal kinase (JNK)-Reference-Cited by-同舟云学术

Alkyl chain substituted 1,9-pyrazoloanthrones exhibit prominent inhibitory effect on c-Jun N-terminal kinase (JNK)

Published:2014 Issue:26 Volume:12 Page:4656-4662
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Prasad Karothu Durga¹²³,Trinath Jamma⁴²³,Biswas Ansuman⁵²³,Sekar Kanagaraj⁶²³,Balaji Kithiganahalli N.⁴²³,Guru Row Tayur N.¹²³

Affiliation:

1. Solid State and Structural Chemistry Unit

2. Indian Institute of Science

3. Bangalore, India

4. Department of Microbiology and Cell Biology

5. Department of Physics

6. Supercomputer Education and Research Centre

Abstract

N-Alkyl substituted pyrazoloanthrone derivatives were synthesized, characterized and tested for theirin vitroinhibitory activity over c-Jun N-terminal kinase (JNK) in regulating inflammation associated disorders.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00548A

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