Development of non-viral vectors for neuronal-targeted delivery of CRISPR-Cas9 RNA-proteins as a therapeutic strategy for neurological disorders-Reference-Cited by-同舟云学术

Development of non-viral vectors for neuronal-targeted delivery of CRISPR-Cas9 RNA-proteins as a therapeutic strategy for neurological disorders

Published:2022 Issue:17 Volume:10 Page:4959-4977
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Shalaby Karim E.¹²^ORCID,Aouida Mustapha¹^ORCID,Gupta Vijay²^ORCID,Abdesselem Houari²,El-Agnaf Omar M. A.¹²^ORCID

Affiliation:

1. Biological and Biomedical Sciences Division, College of Health & Life Sciences, Hamad Bin Khalifa University, Doha, Qatar

2. Neurological Disorder Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation, Doha, Qatar

Abstract

Peptide-based non-viral vectors for CRISPR therapeutic delivery.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D2BM00368F

Reference70 articles.

1. α-Synuclein in Lewy bodies

2. A CRISPR Approach to Neurodegenerative Diseases

3. Targeting neurodegenerative diseases: Drug discovery in a challenging arena

4. Targeting α-synuclein as a therapeutic strategy for Parkinson’s disease

5. CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage

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