Catalyst-free aerobic radical cascade reactions of <i>o</i>-vinylphenylisocyanides with thiols to access 2-thio-substituted quinolines-Reference-Cited by-同舟云学术

Catalyst-free aerobic radical cascade reactions of o-vinylphenylisocyanides with thiols to access 2-thio-substituted quinolines

Published:2022 Issue:23 Volume:9 Page:6484-6489
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Wang Jin¹,Liu Haitao¹,Liu Yaohui¹,Hao Wanting¹,Yang Yingqi¹,Sun Yanan¹,Xu Xianxiu¹^ORCID

Affiliation:

1. College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, China

Abstract

We herein report an efficient and green aerobic radical cascade reaction of o-vinylphenylisocyanides with thiols to access a broad range of 2-thio-substituted quinolines without the need for additional catalysts or oxidants.

Funder

Taishan Scholar Project of Shandong Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO01371A

Reference49 articles.

1. The Ammosamides: Structures of Cell Cycle Modulators from a Marine-DerivedStreptomycesSpecies

2. Synthesis and biological evaluation of quinoline derivatives as potential anti-prostate cancer agents and Pim-1 kinase inhibitors