Structural diversity and biological relevance of benzenoid and atypical ansamycins and their congeners-Reference-Cited by-同舟云学术

Structural diversity and biological relevance of benzenoid and atypical ansamycins and their congeners

Published:2022 Issue:9 Volume:39 Page:1678-1704
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Skrzypczak Natalia¹,Przybylski Piotr¹^ORCID

Affiliation:

1. Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznanskiego 8, 61-614 Poznan, Poland

Abstract

Origin, division, and key structural aspects for biological functionality of ansamycins are discussed. Semisynthetic, mutasynthetic and hybrid approaches, yielding new macrolactams, along their mechanism of action and biological potency are compared.

Funder

Narodowe Centrum Nauki

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NP/D2NP00004K

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