Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules-Reference-Cited by-同舟云学术

Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules

Published:2016 Issue:60 Volume:52 Page:9327-9342
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Opoku-Temeng Clement¹²³⁴⁵,Zhou Jie¹²³⁴⁵,Zheng Yue¹²³⁴⁵,Su Jianmei⁶⁷⁸⁵,Sintim Herman O.¹²³⁴⁵

Affiliation:

1. Department of Chemistry

2. Center for Drug Discovery

3. Purdue University

4. West Lafayette

5. USA

6. Graduate Program in Biochemistry

7. University of Maryland

8. College Park

Abstract

Bacteria utilize nucleotide-based second messengers to regulate a myriad of physiological processes. Small molecules that inhibit nucleotide signaling could have antibacterial properties.

Funder

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC03439J

Reference173 articles.

1. Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP, (p)ppGpp signaling in bacteria and implications in pathogenesis

2. cAMP, c-di-GMP, c-di-AMP and now cGMP: bacteria use them all!

3. Cyclic GMP controls Rhodospirillum centenum cyst development

4. Bacterial nucleotide-based second messengers

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