Tumor-acidity activated surface charge conversion of two-photon fluorescent nanoprobe for enhanced cellular uptake and targeted imaging of intracellular hydrogen peroxide

Author:

Chen Lanlan12345,Xu Shuai67489,Li Wei67489,Ren Tianbing67489ORCID,Yuan Lin67489ORCID,Zhang Shusheng12345ORCID,Zhang Xiao-Bing67489ORCID

Affiliation:

1. Collaborative Innovation Center of Tumor Marker Detection Technology

2. Equipment and Diagnosis-Therapy Integration in Universities of Shandong

3. Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers

4. College of Chemistry and Chemical Engineering

5. Linyi University

6. State Key Laboratory of Chemo/Biosensing and Chemometrics

7. Molecular Science and Biomedicine Laboratory

8. Hunan University

9. Changsha 410082

Abstract

A smart, two-photon fluorescent GC–NABP nanoprobe with pH-dependent surface charge conversion was developed for tumor-targeted visualization of H2O2.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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