Rational design and diversity-oriented synthesis of peptoid-based selective HDAC6 inhibitors-Reference-Cited by-同舟云学术

Rational design and diversity-oriented synthesis of peptoid-based selective HDAC6 inhibitors

Published:2016 Issue:15 Volume:52 Page:3219-3222
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Diedrich D.¹²³⁴,Hamacher A.¹²³⁴,Gertzen C. G. W.¹²³⁴,Alves Avelar L. A.¹²³⁴,Reiss G. J.⁵²³⁴,Kurz T.¹²³⁴,Gohlke H.¹²³⁴,Kassack M. U.¹²³⁴,Hansen F. K.¹²³⁴

Affiliation:

1. Institut für Pharmazeutische und Medizinische Chemie

2. Heinrich-Heine-Universität Düsseldorf

3. 40225 Düsseldorf

4. Germany

5. Institut für Anorganische Chemie und Strukturchemie

Abstract

A mini library of selective HDAC6 inhibitors with peptoid-based cap groups was synthesized using an efficient multicomponent approach.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C5CC10301K

Reference21 articles.

1. Epigenetics—An Epicenter of Gene Regulation: Histones and Histone-Modifying Enzymes

2. Chemical phylogenetics of histone deacetylases

3. HDAC family: What are the cancer relevant targets?

4. Inside HDAC with HDAC inhibitors

5. Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

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