Novel histone deacetylase 6 inhibitors using benzimidazole as caps for cancer treatment-Reference-Cited by-同舟云学术

Novel histone deacetylase 6 inhibitors using benzimidazole as caps for cancer treatment

Published:2023 Issue:16 Volume:47 Page:7622-7631
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Nguyen Phuong Hong¹²,Hue Bui Thi Buu³,Pham Minh Quan⁴⁵^ORCID,Hoa Tran Phuong¹²,Tran Quang De³^ORCID,Jung Hosun¹²,Hieu Le Trong³,Quoc Nguyen Cuong³^ORCID,Quang Hong Vinh³,Quy Nguyen Phu³,Yoo Hye Jin¹,Yang Su-Geun¹²^ORCID

Affiliation:

1. Department of Biomedical Science, BK21 FOUR Program in Biomedical Science and Engineering, Inha University College of Medicine, Incheon 22212, Korea

2. Inha Institute of Aerospace Medicine, Inha University College of Medicine, Incheon 22332, Korea

3. College of Natural Sciences, Can Tho University, Can Tho city, Vietnam

4. Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology, Ha Noi, Vietnam

5. Graduate University of Science and Technology, Vietnam Academy of Science and Technology, Ha Noi, Vietnam

Abstract

A cap of benzimidazole and a four carbon-chain-containing thioether linker is a superior HDAC6 inhibitor to belinostat.

Funder

Ministry of Education and Training

National Research Foundation of Korea

Daewoong Pharmaceutical Company

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D2NJ05731J

Reference48 articles.

1. Cancer Epigenetics: From Mechanism to Therapy

2. Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents

3. Exploring structural requirements of isoform selective histone deacetylase inhibitors: a comparative in silico study

4. Isoform-selective histone deacetylase inhibitors: the trend and promise of disease treatment

5. Histone deacetylase inhibitors (HDACIs). Structure-activity relationships: history and new QSAR perspectives

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