Spirodesertols A and B, two highly modified spirocyclic diterpenoids with an unprecedented 6-isopropyl-3H-spiro[benzofuran-2,1′-cyclohexane] motif from Salvia deserta-Reference-Cited by-同舟云学术

Spirodesertols A and B, two highly modified spirocyclic diterpenoids with an unprecedented 6-isopropyl-3H-spiro[benzofuran-2,1′-cyclohexane] motif from Salvia deserta

Published:2020 Issue:20 Volume:7 Page:3137-3145
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zheng Guijuan¹²³⁴⁵,Kadir Abdukriem¹²³⁴⁵,Zheng Xiaofeng⁶⁷⁸⁹¹⁰,Jin Pengfei⁶⁷⁸⁹¹⁰,Liu Junjun⁶⁷⁸⁹¹⁰^ORCID,Maiwulanjiang Maitinuer¹²³⁴⁵,Yao Guangmin¹²³⁴⁵^ORCID,Aisa Haji Akber¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Plant Resources and Chemistry of Arid Zone

2. Xinjiang Technical Institute of Physics and Chemistry

3. Chinese Academy of Sciences

4. Urumqi, Xinjiang 830011

5. People' Republic of China

6. Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation

7. School of Pharmacy

8. Tongji Medical College

9. Huazhong University of Science and Technology

10. Wuhan, Hubei 430030

Abstract

Two highly modified spirocyclic diterpenoids with an unprecedented 6-isopropyl-3H-spiro[benzofuran-2,1′-cyclohexane] motif and four new icetexane diterpenoids were isolated from Salvia deserta. 1 showed more potent cytotoxicity than cis-platin.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO00735H

Reference45 articles.

1. Quinone diterpenes from Salvia species: chemistry, botany, and biological activity

2. Bioactive phytochemicals from shoots and roots of Salvia species

3. Isolation, structural elucidation, and synthetic study of salviyunnanone A, an abietane derived diterpenoid with a 7/5/6/3 ring system from Salvia yunnanensis