Sequence information transfer using covalent template-directed synthesis

Author:

Núñez-Villanueva Diego1234ORCID,Ciaccia Maria1234,Iadevaia Giulia1234ORCID,Sanna Elena1234,Hunter Christopher A.1234ORCID

Affiliation:

1. Department of Chemistry

2. University of Cambridge

3. Cambridge

4. UK

Abstract

Kinetically inert ester bonds were used to attach monomers to a template, dictating the sequence of the polymer product.

Funder

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Reference53 articles.

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3. Tuning the activity of an enzyme for unusual environments: sequential random mutagenesis of subtilisin E for catalysis in dimethylformamide.

4. Unnatural Selection in Chemical Systems

5. In vitro selection of RNA molecules that bind specific ligands

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