Restoring the electrical microenvironment using ferroelectric nanocomposite membranes to enhance alveolar ridge regeneration in a mini-pig preclinical model

Author:

Li Yiping123,Meng Yanze1,Bai Yunyang3,Wang Yijun1,Wang Jiaqi2,Heng Boonchin4,Wei Jinqi5,Jiang Xi6,Gao Min37,Zheng Xiaona37ORCID,Zhang Xuehui17ORCID,Deng Xuliang37

Affiliation:

1. Department of Dental Materials & Dental Medical Devices Testing Center, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China

2. Department of Prosthodontics, Xiangya Stomatological Hospital & School of Stomatology, Central South University, Changsha, 410078, P. R. China

3. Department of Geriatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China

4. Central Laboratory, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China

5. First Clinical Division, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China

6. Department of Oral Implantology, Peking University School and Hospital of Stomatology, Beijing, 100081, P. R. China

7. National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, NMPA Key Laboratory for Dental Materials, Beijing Laboratory of Biomedical Materials & Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing 100081, P. R. China

Abstract

The maintenance and incremental growth of the alveolar bone at the tooth extraction site, to achieve the required height and width for implant restoration, remains a major clinical challenge.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Key Technologies Research and Development Program

Natural Science Foundation of Hunan Province

School of Stomatology, Peking University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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