Atropisomerism in 3-arylthiazolidine-2-thiones. A combined dynamic NMR and dynamic HPLC study

Author:

Ciogli A.1234,Vivek Kumar S.56789,Mancinelli M.1011124,Mazzanti A.1011124ORCID,Perumal S.56789,Severi C.1011124ORCID,Villani C.1234ORCID

Affiliation:

1. Department of Chemistry and Technologies of Drug

2. Sapienza University of Rome

3. I-00185 Rome

4. Italy

5. Department of Organic Chemistry

6. School of Chemistry

7. Madurai Kamaraj University

8. Madurai-625021

9. India

10. Department of Industrial Chemistry “Toso Montanari”

11. University of Bologna

12. I-40136 Bologna

Abstract

Atropisomerism was observed on sterically hindered 3-arylthiazolidine-2-thiones, whose rotational energy barriers were measured using dynamic NMR and dynamic HPLC.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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