Local administration of stem cell-derived extracellular vesicles in a thermoresponsive hydrogel promotes a pro-healing effect in a rat model of colo-cutaneous post-surgical fistula-Reference-Cited by-同舟云学术

Local administration of stem cell-derived extracellular vesicles in a thermoresponsive hydrogel promotes a pro-healing effect in a rat model of colo-cutaneous post-surgical fistula

Published:2021 Issue:1 Volume:13 Page:218-232
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Berger Arthur¹²³⁴⁵^ORCID,Araújo-Filho Irami⁶⁷⁸⁹,Piffoux Max¹⁰⁵¹¹¹²¹³,Nicolás-Boluda Alba¹⁰⁵¹¹¹²¹³^ORCID,Grangier Alice¹⁰⁵¹¹¹²¹³,Boucenna Imane¹⁰⁵¹¹¹²¹³,Real Caroline Cristiano¹⁴¹⁵¹⁶¹⁷¹⁸^ORCID,Marques Fabio Luiz Navarro¹⁴¹⁵¹⁶¹⁷¹⁸^ORCID,de Paula Faria Daniele¹⁴¹⁵¹⁶¹⁷¹⁸,do Rego Amália Cinthia Meneses¹⁹²⁰⁹,Broudin Chloe²¹²²²³⁵²⁴,Gazeau Florence¹⁰⁵¹¹¹²¹³^ORCID,Wilhelm Claire¹⁰⁵¹¹¹²¹³^ORCID,Clément Olivier²⁵²¹²³²⁴¹³,Cellier Christophe²⁶²¹²³⁵²⁴,Buchpiguel Carlos Alberto¹⁴¹⁵¹⁶¹⁷¹⁸^ORCID,Rahmi Gabriel¹²³⁴⁵,Silva Amanda K. A.¹⁰⁵¹¹¹²¹³^ORCID

Affiliation:

1. Laboratoire Imagerie de l'Angiogénèse

2. Plateforme d'Imagerie du Petit Animal

3. PARCC

4. INSERM U970

5. Université de Paris

6. Universidade Federal do Rio Grande do Norte

7. Hospital Universitário Onofre Lopes

8. 59.012-300 Natal – RN

9. Brazil

10. Laboratoire Matière et Systèmes Complexes (MSC)

11. UMR 7057 CNRS

12. 75205 Paris Cedex 13

13. France

14. Laboratory of Nuclear Medicine (LIM-43)

15. Departamento de Radiologia e Oncologia

16. Faculdade de Medicina

17. Universidade de Sao Paulo

18. Sao Paulo

19. Liga Norte Riograndense Contra o Câncer

20. Natal – RN

21. Hôpital Européen Georges Pompidou

22. Department of Pathology

23. Assistance Publique des Hôpitaux de Paris

24. Paris

25. Department of Radiology

26. Gastro-Enteroloy and Endoscopy Department

Abstract

Local minimally-invasive EV delivery on a thermo-actuated PF-127 gel enhanced EV residence time in colo-cutaneous fistulas promoting a therapeutic effect.

Funder

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D0NR07349K

Reference67 articles.

1. Paracrine Mechanisms of Mesenchymal Stem Cell-Based Therapy: Current Status and Perspectives

2. Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

3. Membrane Microparticles: Two Sides of the Coin