GC-MS analysis of phytoconstituents from Ruellia prostrata and Senna tora and identification of potential anti-viral activity against SARS-CoV-2

Author:

Alam Rahat12ORCID,Imon Raihan Rahman12ORCID,Kabir Talukder Md. Enamul12ORCID,Akhter Shahina23ORCID,Hossain Md. Alam4,Ahammad Foysal25ORCID,Rahman Md. Mashiar1ORCID

Affiliation:

1. Molecular and Cellular Biology Laboratory, Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore-7408, Bangladesh

2. Laboratory of Computational Biology, Biological Solution Centre (BioSol Centre), Jashore-7408, Bangladesh

3. Department of Biochemistry and Biotechnology, University of Science and Technology Chittagong (USTC), Foy's Lake, Khulshi, Chittagong-4202, Bangladesh

4. Department of Computer Science and Engineering, Jashore University of Science and Technology, Jashore-7408, Bangladesh

5. Department of Biology, Faculty of Science, King Abdul-Aziz University, Jeddah-21589, Saudi Arabia

Abstract

Protease (Mpro) of SARS-CoV-2 has been identified as being able to hinder the replication process of the virus. Using GC-MS analytical methods, phytochemicals were identified from different medicinal plants that resulted in inhibitory activity of the molecules against Mpro.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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