Formal [4 + 1] cycloaddition of o-quinone methides: facile synthesis of dihydrobenzofurans-Reference-Cited by-同舟云学术

Formal [4 + 1] cycloaddition of o-quinone methides: facile synthesis of dihydrobenzofurans

Published:2015 Issue:20 Volume:5 Page:14953-14957
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Lei Xiantao¹²³⁴⁵,Jiang Chun-Huan¹²³⁴⁵,Wen Xiaoan¹²³⁴⁵,Xu Qing-Long¹²³⁴⁵,Sun Hongbin¹²³⁴⁵

Affiliation:

1. Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases

2. State Key Laboratory of Natural Medicines

3. Center of Drug Discovery

4. China Pharmaceutical University

5. Nanjing 210009

Abstract

An efficient and straightforward method for the rapid synthesis of 2-substituted dihydrobenzofurans has been developed via reaction of sulfur ylides with o-quinone methides (o-QMs).

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C4RA17003B

Reference46 articles.

1. Taming Reactive Phenol Tautomers and o-Quinone Methides with Transition Metals: A Structure−Reactivity Relationship

2. Syntheses of chromenes and chromanesvia o-quinone methide intermediates

3. Quinone Methides ed. S. E. Rokita, Wiley, New York, 2009

4. BINOL−Amino Acid Conjugates as Triggerable Carriers of DNA-Targeted Potent Photocytotoxic Agents

5. Quinone Methides Tethered to Naphthalene Diimides as Selective G-Quadruplex Alkylating Agents

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