QSAR-guided semi-synthesis and in vitro validation of antiplasmodial activity in ursolic acid derivatives-Reference-Cited by-同舟云学术

QSAR-guided semi-synthesis and in vitro validation of antiplasmodial activity in ursolic acid derivatives

Published:2015 Issue:41 Volume:5 Page:32133-32143
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kalani Komal¹²³⁴⁵,Cheema Harveer Singh⁶²³⁴⁵,Tripathi Himanshu⁷²³⁴⁵,Khan Feroz⁷²³⁴⁵,Daroker M. P.⁶²³⁴⁵,Srivastava Santosh Kumar¹²³⁴⁵

Affiliation:

1. Medicinal Chemistry Department

2. CSIR-Central Institute of Medicinal and Aromatic Plants

3. Lucknow-226015

4. India

5. Academy of Scientific and Innovative Research (AcSIR)

6. Molecular Bioprospection Department

7. Metabolic & Structural Biology Department

Abstract

As a part of antimalarial drug discovery programme, a QSAR model was developed for the prediction of antiplasmodial activity in ursolic acid derivatives, followed by semi-synthesis of virtually active derivatives and their biological evaluation.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C4RA13709D

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