Manipulating polyketide stereochemistry by exchange of polyketide synthase modules-Reference-Cited by-同舟云学术

Manipulating polyketide stereochemistry by exchange of polyketide synthase modules

Published:2020 Issue:84 Volume:56 Page:12749-12752
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Massicard Jean-Malo¹²³⁴⁵,Soligot Claire¹⁶⁷⁴⁵,Weissman Kira J.¹²³⁴⁵^ORCID,Jacob Christophe¹²³⁴⁵^ORCID

Affiliation:

1. Université de Lorraine

2. CNRS

3. IMoPA

4. F-54000 Nancy

5. France

6. UR AFPA

7. USC 340 INRAE

Abstract

Exchange of polyketide synthase (PKS) modules by genetic engineering leads to efficient modification of polyketide stereochemistry.

Funder

Centre National de la Recherche Scientifique

Université de Lorraine

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/D0CC05068G

Reference38 articles.

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2. Natural product derived privileged scaffolds in drug discovery

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5. Polyketide biosynthesis: a millennium review

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