Studying a Bottleneck of Multimodular Polyketide Synthase Processing: the Polyketide Structure-Dependent Performance of Ketoreductase Domains-Reference-Cited by-同舟云学术

Studying a Bottleneck of Multimodular Polyketide Synthase Processing: the Polyketide Structure-Dependent Performance of Ketoreductase Domains

Published:2022-04-12 Issue:5 Volume:17 Page:1030-1037
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Schröder Marius¹²,Roß Theresa¹,Hemmerling Franziska¹²,Hahn Frank¹²^ORCID

Affiliation:

1. Professur für Organische Chemie (Lebensmittelchemie), Fakultät für Biologie, Chemie und Geowissenschaften, Department of Chemistry, Universität Bayreuth, 95447 Bayreuth, Germany

2. Biomolekulares Wirkstoffzentrum, Leibniz Universität Hannover, 30167 Hannover, Germany

Funder

Boehringer Ingelheim Stiftung

Verband der Chemischen Industrie

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.2c00047

Reference35 articles.

1. Combinatorial biosynthesis of reduced polyketides

2. Polyketide biosynthesis: a millennium review

3. The Biosynthetic Logic of Polyketide Diversity

4. The Uncommon Enzymology of Cis-Acyltransferase Assembly Lines

5. Engineering strategies for rational polyketide synthase design

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