Substitution of unsaturated lipid chains by thioether-containing lipid chains in cationic amphiphiles: physicochemical consequences and application for gene delivery-Reference-Cited by-同舟云学术

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Substitution of unsaturated lipid chains by thioether-containing lipid chains in cationic amphiphiles: physicochemical consequences and application for gene delivery

Published:2019 Issue:14 Volume:17 Page:3609-3616
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Bouraoui Amal¹²³⁴,Berchel Mathieu¹²³⁴^ORCID,Ghanem Rosy⁵²⁶⁷⁸,Vié Véronique⁹¹⁰¹¹⁴,Paboeuf Gilles⁹¹⁰¹¹⁴,Deschamps Laure¹²³⁴,Lozach Olivier¹²³⁴^ORCID,Le Gall Tony⁵²⁶⁷⁸^ORCID,Montier Tristan⁵²⁶⁷⁸^ORCID,Jaffrès Paul-Alain¹²³⁴^ORCID

Affiliation:

1. CEMCA UMR CNRS 6521

2. Université de Brest

3. F-29238 Brest

4. France

5. INSERM UMR 1078

6. IBSAM

7. UFR Médecine et Sciences de la Santé

8. CHRU Brest

9. Univ Rennes

10. CNRS

11. F-35000 Rennes

Abstract

New thioether-containing amphiphiles were designed, characterized and applied for gene delivery.

Funder

Association Vaincre la Mucoviscidose

Association Française contre les Myopathies

Centre National de la Recherche Scientifique

Institut National de la Santé et de la Recherche Médicale

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB00473D

Reference28 articles.

1. Progress in Cationic Lipid-Mediated Gene Transfection: A Series of Bio- Inspired Lipids as an Example

2. Nonviral Vectors for Gene Delivery

3. Synthetic vectors for gene delivery: An overview of their evolution depending on routes of administration.

4. Highly efficient gene transfer into hepatocyte-like HepaRG cells: New means for drug metabolism and toxicity studies

5. A Novel Cationic Lipophosphoramide with Diunsaturated Lipid Chains: Synthesis, Physicochemical Properties, and Transfection Activities

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2. A cationic lipid with advanced membrane fusion performance for pDNA and mRNA delivery;Journal of Materials Chemistry B;2023

3. Phosphonodithioformate-amine coupling reaction: from basic discovery to application for the functionalization of liposomes;Phosphorus, Sulfur, and Silicon and the Related Elements;2021-12-14

4. Phosphonodithioester–Amine Coupling as a Key Reaction Step for the Design of Cationic Amphiphiles Used for Gene Delivery;Molecules;2021-12-11

5. DNA nuclear targeting sequences for enhanced non-viral gene transfer: An in vitro and in vivo study;Molecular Therapy - Nucleic Acids;2021-06

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