N-Chloroamines as substrates for metal-free photochemical atom-transfer radical addition reactions in continuous flow-Reference-Cited by-同舟云学术

N-Chloroamines as substrates for metal-free photochemical atom-transfer radical addition reactions in continuous flow

Published:2021 Issue:12 Volume:6 Page:2434-2441
ISSN:2058-9883
Container-title:Reaction Chemistry & Engineering
language:en
Short-container-title:React. Chem. Eng.

Author:

Steiner Alexander¹²^ORCID,de Frutos Oscar³,Rincón Juan A.³,Mateos Carlos³^ORCID,Williams Jason D.¹²^ORCID,Kappe C. Oliver¹²^ORCID

Affiliation:

1. Center for Continuous Flow Synthesis and Processing (CC FLOW), Research Center Pharmaceutical Engineering GmbH (RCPE), Inffeldgasse 13, 8010 Graz, Austria

2. Institute of Chemistry, NAWI Graz, University of Graz, Heinrichstrasse 28, 8010 Graz, Austria

3. Centro de Investigación Lilly S.A., Avda. de la Industria 30, 28108 Alcobendas-Madrid, Spain

Abstract

Photochemical ATRA reactions of N-chloroamines represent an efficient and green method of alkene functionalization. N-Chloroamine generation, purification and reaction in flow enables an efficient process, with a variety of irradiation wavelengths.

Funder

Österreichische Forschungsförderungsgesellschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RE/D1RE00429H

Reference61 articles.

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