A thermally and water activated shape memory gelatin physical hydrogel, with a gel point above the physiological temperature, for biomedical applications

Abstract

In this study, a science based approach is taken to monitor the variation of the properties, bioactivity and hydrogel formation behavior of gelatin upon functionalization with Ureido Pyrimidinone hexyl isocyanate (UPy synthon), which results in reversible physical network formation.