Detection of lipase activity in human serum based on a ratiometric fluorescent probe
Author:
Affiliation:
1. Departments of Pharmacology and Medicinal Chemistry
2. Qingdao University School of Pharmacy
3. Qingdao 266071
4. China
5. Department of Emergency Internal Medicine
6. The Affiliated Hospital of Qingdao University
7. Qingdao
Abstract
CARA can monitor lipase activity through hydrolyzing the ester bond to interrupt the FRET process.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Shandong Province
National Key Research and Developmen
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2021/NJ/D1NJ01155C
Reference36 articles.
1. Amylase and lipase in the emergency department evaluation of acute pancreatitis
2. The level of the zymogen granule protein GP2 is elevated in a rat model for acute pancreatitis
3. Organ Failure Due to Systemic Injury in Acute Pancreatitis
4. Diagnosing acute pancreatitis—Clinical and radiological characterisation of patients without threefold increase of serum lipase
5. Amylase, Lipase, and Acute Pancreatitis in People With Type 2 Diabetes Treated With Liraglutide: Results From the LEADER Randomized Trial
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