Visualizing the down-regulation of hTERT mRNA expression using gold-nanoflare probes and verifying the correlation with cancer cell apoptosis-Reference-Cited by-同舟云学术

Visualizing the down-regulation of hTERT mRNA expression using gold-nanoflare probes and verifying the correlation with cancer cell apoptosis

Published:2019 Issue:9 Volume:144 Page:2994-3004
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Sun Hongxiao¹²³⁴,Hong Min¹²³⁴^ORCID,Yang Qiangqiang¹²³⁴,Li Chuan¹²³⁴,Zhang Guangzhi¹²³⁴,Yue Qiaoli¹²³⁴,Ma Yanhua¹²³⁴,Li Xia¹²³⁴,Li Chen-Zhong¹²³⁴⁵^ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering

2. Liaocheng University

3. Liaocheng 252059

4. P. R. China

5. Nanobioengineering/Bioelectronics Laboratory

Abstract

A locked nucleic acid-functionalized gold nanoparticle flare probe was designed to achieve in situ monitoring and regulating intracellular hTERT mRNA which also induced the apoptosis of cancer cells.

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Natural Science Foundation of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/AN/C9AN00204A

Reference54 articles.

1. Effects of phosphorothioate anti-sense oligodeoxynucleotides on colorectal cancer cell growth and telomerase activity