Anticancer therapeutic effect of cerium-based nanoparticles: known and unknown molecular mechanisms

Author:

Amaldoss Maria John Newton12ORCID,Mehmood Rashid3ORCID,Yang Jia-Lin1,Koshy Pramod2ORCID,Kumar Naresh4ORCID,Unnikrishnan Ashwin1ORCID,Sorrell Charles C.2ORCID

Affiliation:

1. Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, UNSW Sydney, Sydney, NSW 2052, Australia

2. School of Materials Science and Engineering, UNSW Sydney, Sydney, NSW 2052, Australia

3. School of Chemical Engineering, UNSW Sydney, Sydney, NSW 2052, Australia

4. School of Chemistry, UNSW Sydney, Sydney, NSW 2052, Australia

Abstract

Summary of ROS-dependent and ROS-independent anticancer effects of Ce-based nanoparticles in the cellular environment, categorized according to materials-based and radiation-assisted effects.

Funder

National Health and Medical Research Council

Leukemia and Lymphoma Society

Snowdome Foundation

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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