Double quick, double click reversible peptide “stapling”-Reference-Cited by-同舟云学术

Double quick, double click reversible peptide “stapling”

Published:2017 Issue:7 Volume:8 Page:5166-5171
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Grison Claire M.¹²³⁴⁵^ORCID,Burslem George M.¹²³⁴⁵^ORCID,Miles Jennifer A.¹²³⁴⁵^ORCID,Pilsl Ludwig K. A.¹²³⁴⁵,Yeo David J.¹²³⁴⁵,Imani Zeynab¹²³⁴⁵,Warriner Stuart L.¹²³⁴⁵^ORCID,Webb Michael E.¹²³⁴⁵^ORCID,Wilson Andrew J.¹²³⁴⁵^ORCID

Affiliation:

1. School of Chemistry

2. University of Leeds

3. Leeds LS2 9JT

4. UK

5. Astbury Centre For Structural Molecular Biology

Abstract

A versatile, rapid and reversible approach to constrain peptides in a bioactive helical conformation and bearing a functional handle for inhibition of protein–protein interactions is described.

Funder

H2020 European Research Council

Wellcome Trust

Leverhulme Trust

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC01342F

Reference68 articles.