SERS-based nanostrategy for rapid anemia diagnosis

Author:

Muhammad Pir1234ORCID,Hanif Sumaira1234ORCID,Yan Jiliang12345,Rehman Fawad Ur1234ORCID,Wang Jiefei1234,Khan Maqbool6784,Chung Roger910111213,Lee Albert910111213,Zheng Meng1234ORCID,Wang Yuling14151216ORCID,Shi Bingyang12349ORCID

Affiliation:

1. Henan-Macquarie University Joint Centre for Biomedical Innovation

2. School of Life Sciences Henan University Kaifeng

3. Henan 475004

4. China

5. Department of Clinical Laboratory

6. State Key Laboratory for Novel Software Technology

7. Nanjing University

8. Nanjing 210023

9. Centre for Motor Neuron Disease Research

10. Department of Biomedical Sciences

11. Faculty of Medicine & Health Sciences

12. Macquarie University

13. Sydney, NSW

14. Department of Molecular Sciences

15. Faculty of Science and Engineering

16. Sydney 2109 Australia

Abstract

A novel multimodal anemia diagnosis assay was developed using the SERS and compared with the routinely used clinical assays. The dual-target (iron ion/metalloprotein) capturing efficiencyviastrong organic cyanide affinity was utilized for whole blood analyses.

Funder

National Natural Science Foundation of China

Judith Jane Mason and Harold Stannett Williams Memorial Foundation

National Health and Medical Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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