Towards a general ruthenium-catalyzed hydrogenation of secondary and tertiary amides to amines
Author:
Affiliation:
1. Leibniz-Institut für Katalyse e.V.
2. 18059 Rostock
3. Germany
4. Istituto di Chimica Biomolecolare
5. Consiglio Nazionale delle Ricerche
Abstract
[Ru(acac)3]/Triphos in combination with Yb(OTf)3 constitutes an improved catalyst system for the hydrogenation of aliphatic and aromatic secondary and tertiary amides.
Funder
Ramón Areces Foundation
Bundesministerium für Bildung und Forschung
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/SC/C5SC04671H
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2. Amines: Synthesis, Properties and Applications, ed. S. A. Lawerence, Cambridge University, Cambridge, 2006
3. Analysis of the reactions used for the preparation of drug candidate molecules
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