Naturally occurring quaternary benzo[c]phenanthridine alkaloids selectively stabilize G-quadruplexes-Reference-Cited by-同舟云学术

Naturally occurring quaternary benzo[c]phenanthridine alkaloids selectively stabilize G-quadruplexes

Published:2018 Issue:33 Volume:20 Page:21772-21782
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Jarosova Petra¹²³⁴,Paroulek Petr¹²³⁴,Rajecky Michal¹²³⁴,Rajecka Veronika¹²³⁴,Taborska Eva⁵²³⁴,Eritja Ramon⁶⁷⁸⁹^ORCID,Aviñó Anna⁶⁷⁸⁹,Mazzini Stefania¹⁰¹¹¹²¹³¹⁴,Gargallo Raimundo¹⁵¹⁶¹⁷⁹^ORCID,Taborsky Petr¹²³⁴^ORCID

Affiliation:

1. Faculty of Science

2. Masaryk University

3. Brno 62500

4. Czech Republic

5. Faculty of Medicine

6. Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

7. CIBER-BBN

8. E-08034 Barcelona

9. Spain

10. Department of Food

11. Environmental and Nutritional Sciences (DEFENS)

12. Section of Chemical and Biomolecular Sciences

13. University of Milan

14. Milan 20133

15. Department of Chemical Engineering and Analytical Chemistry

16. University of Barcelona

17. 08028 Barcelona

Abstract

In this work, the interaction of six natural benzo[c]phenanthridine alkaloids (macarpine, sanguilutine, sanguirubine, chelerythrine, sanguinarine and chelirubine) with parallel and antiparallel G-quadruplex DNA structures was studied.

Funder

Ministerstvo Školství, Mládeže a Tělovýchovy

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CP/C8CP02681E

Reference51 articles.

1. Interaction of oligonucleotides with benzo[c]phenanthridine alkaloid sanguilutine

2. Antiproliferative activity of O4-benzo[c]phenanthridine alkaloids against HCT-116 and HL-60 tumor cells

3. Sanguinarine: an evaluation of in vivo cytogenetic activity

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