Chelerythrine Chloride is an Affinity-Labeling Inactivator of CYP3A4 by Modification of Cysteine239-Reference-Cited by-同舟云学术

Chelerythrine Chloride is an Affinity-Labeling Inactivator of CYP3A4 by Modification of Cysteine239

Published:2024-02-08 Issue:4 Volume:67 Page:2802-2811
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mao Xu¹²,Zhao Guode³,Wang Qian³⁴,He Junqi¹,Liu Ying¹,Liu Ting¹,Li Weiwei¹^ORCID,Peng Ying³,Zheng Jiang¹³^ORCID

Affiliation:

1. State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang 550004, Guizhou, PR China

2. Department of Pharmaceutical Analysis, College of Pharmacy, Mudanjiang Medical University, Mudanjiang 157011, PR China

3. Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning, PR China

4. Shuangyashan Disease Control and Prevention Center, Shuangyashan 155100, PR China

Funder

Natural Science Foundation of Guizhou Province

Natural Science Foundation of Heilongjiang Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01943

Reference28 articles.

1. HPLC quantification of seven quaternary benzo[c]phenanthridine alkaloids in six species of the family Papaveraceae

2. Identification of metabolites of selected benzophenanthridine alkaloids and their toxicity evaluation

3. Nitidine Chloride Is a Mechanism-Based Inactivator of CYP2D6

4. Influence of Solvent Polarity and DNA-Binding on Spectral Properties of Quaternary Benzo[c]phenanthridine Alkaloids

5. Naturally occurring quaternary benzo[c]phenanthridine alkaloids selectively stabilize G-quadruplexes