Highly diastereoselective construction of novel dispiropyrrolo[2,1-a]isoquinoline derivativesviamulticomponent 1,3-dipolar cycloaddition of cyclic diketones-based tetrahydroisoquinoliniumN-ylides-Reference-Cited by-同舟云学术

Highly diastereoselective construction of novel dispiropyrrolo[2,1-a]isoquinoline derivativesviamulticomponent 1,3-dipolar cycloaddition of cyclic diketones-based tetrahydroisoquinoliniumN-ylides

Published:2019 Issue:20 Volume:9 Page:11082-11091
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Boudriga Sarra¹²³⁴⁵^ORCID,Haddad Saoussen¹²³⁴⁵,Askri Moheddine¹²³⁴⁵^ORCID,Soldera Armand⁶⁷⁸⁹,Knorr Michael¹⁰¹¹¹²¹³^ORCID,Strohmann Carsten¹⁴¹⁵¹⁶,Golz Christopher¹⁴¹⁵¹⁶

Affiliation:

1. Laboratory of Heterocyclic Chemistry Natural Product and Reactivity/CHPNR

2. Department of Chemistry

3. Faculty of Science of Monastir

4. 5000 Monastir

5. Tunisia

6. Departement of Chemistry

7. Quebec Center for Functional Materials University of Sherbrooke

8. Sherbrooke

9. Canada J1K 2R1

10. Institut UTINAM - UMR CNRS 6213

11. Université Bourgogne Franche-Comté

12. 25030 Besançon

13. France

14. Technische Universität Dortmund, Anorganische Chemie

15. 44221 Dortmund

16. Germany

Abstract

A new series of dispiropyrrolo[2,1-a]isoquinoline derivatives was synthesized by multicomponent 1,3-dipolar cycloaddition reaction of tetrahydroisoquinoliniumN-ylides and (E)-3-arylidene-1-phenyl-pyrrolidine-2,5-diones.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C8RA09884K

Reference83 articles.

1. Molecular Determinants of Topoisomerase I Poisoning by Lamellarins: Comparison with Camptothecin and Structure−Activity Relationships

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4. Novel bioactive isoquinoline alkaloids from Carduus crispus

5. Lamellarin α 20-Sulfate, an Inhibitor of HIV-1 Integrase Active against HIV-1 Virus in Cell Culture

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