Room-temperature C–H bond alkynylation by merging cobalt and photocatalysts

Author:

Mandal Rajib1,Barsu Nagaraju1,Garai Bholanath1,Das Abir1,Perekalin Dmitry2ORCID,Sundararaju Basker1ORCID

Affiliation:

1. Department of chemistry, Indian Institute of technology Kanpur, Kanpur, Uttar Pradesh, 208016, India

2. A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilova str., Moscow, Russia

Abstract

A new protocol is developed for the mono- and bis-ortho-C–H alkynylation of easily accessible benzamide derivatives using alkynyl bromides at room temperature by merging cobalt and photocatalysts.

Funder

Russian Foundation for Basic Research

Department of Science and Technology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Reference51 articles.

1. Introduction: CH Activation

2. P. H.Dixneuf and H.Doucet , C–H Bond Activation and Catalytic Functionalization I , Springer , 2016 , pp. 1–76

3. C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

4. Transition metal-catalyzed C–H bond functionalizations by the use of diverse directing groups

5. M.Halka and B.Nordstrom , Transition Metals; Facts on file , London , 2011

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