[3+2] regioselective annulation reaction of 2-arylidene-1,3-indandiones towards synthesis of spirocyclopentenes: understanding the mechanism of γ-attack vs. α-attack using DFT studies-Reference-Cited by-同舟云学术

[3+2] regioselective annulation reaction of 2-arylidene-1,3-indandiones towards synthesis of spirocyclopentenes: understanding the mechanism of γ-attack vs. α-attack using DFT studies

Published:2021 Issue:61 Volume:11 Page:38648-38653
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Anwar Shaik¹²^ORCID,Lin Li-Tzu²,Srinivasadesikan V.¹,Gudise Veera Babu¹,Chen Kwunmin²^ORCID

Affiliation:

1. Division of Chemistry, Department of Sciences and Humanities, Vignan's Foundation for Science Technology and Research-VFSTR (Deemed to be University), Vadlamudi-522 213, Guntur, Andhra Pradesh, India

2. Department of Chemistry, National Taiwan Normal University, 88 Sec. 4, TingChow Road, Taipei, Taiwan 116, ROC

Abstract

A [3+2] annulation protocol for the construction of functionalized spirocyclopentenes utilizing 1,3-indanedione derived benzylidene-1,3-indanedione and ethyl-2,3-butadienoate at room temperature was developed.

Funder

Science and Engineering Research Board

Ministry of Science and Technology of the People's Republic of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA07165C

Reference84 articles.

1. Phosphine-Catalyzed Cycloaddition of 2,3-Butadienoates or 2-Butynoates with Electron-Deficient Olefins. A Novel [3 + 2] Annulation Approach to Cyclopentenes

2. Application of a New Chiral Phosphepine to the Catalytic Asymmetric Synthesis of Highly Functionalized Cyclopentenes That Bear an Array of Heteroatom-Substituted Quaternary Stereocenters