Localized NIR-II photo-immunotherapy through the combination of photothermal ablation and in situ generated interleukin-12 cytokine for efficiently eliminating primary and abscopal tumors-Reference-Cited by-同舟云学术

Localized NIR-II photo-immunotherapy through the combination of photothermal ablation and in situ generated interleukin-12 cytokine for efficiently eliminating primary and abscopal tumors

Published:2021 Issue:3 Volume:13 Page:1745-1758
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Lin Xinyi¹²³⁴⁵^ORCID,Wang Xiaoyan⁶⁷⁸⁹,Li Jiong¹²³⁴⁵,Cai Linsheng¹⁰¹¹¹²¹³,Liao Fangyu¹⁰¹¹¹²¹³¹⁴,Wu Ming¹⁰¹¹¹²¹³¹⁴^ORCID,Zheng Dongye¹⁰¹¹¹²¹³,Zeng Yongyi¹⁰¹¹¹²¹³¹⁴,Zhang Zhenxi¹²³⁴⁵,Liu Xiaolong¹⁰¹¹¹²¹³¹⁴^ORCID,Wang Jing¹²³⁴⁵,Yao Cuiping¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Biomedical Information Engineering of Ministry of Education

2. Institute of Biomedical Analytical Technology and Instrumentation

3. School of Life Science and Technology

4. Xi'an Jiaotong University

5. Xi'an 710049

6. School of Life Sciences

7. Fujian Agriculture and Forestry University

8. Fuzhou 350002

9. P.R. China

10. The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province

11. Mengchao Hepatobiliary Hospital of Fujian Medical University

12. Fuzhou 350025

13. P. R. China

14. Mengchao Med-X Center

Abstract

A novel photothermal agent (PTA) and gene co-delivery nanosystem (CSP@IL-12) for tumor localized NIR-II PTT and in situ immunotherapy through local generation of IL-12 cytokine.

Funder

National Natural Science Foundation of China

Fujian Provincial Department of Science and Technology

Science Foundation of Fuzhou

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D0NR06182D

Reference57 articles.

1. Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer