Visualizing mitochondria and mouse intestine with a fluorescent complex of a naphthalene-based dipolar dye and serum albumin

Author:

An Jong Min12345,Moon Heejo67895,Kim Yejin101181213,Kang Sangrim1412345,Kim Youngseo615165,Jung Yuna12345,Park Sungnam615165ORCID,Verwilst Peter1718192021,Kim B. Moon67895ORCID,Kang Jae Seung101181213,Kim Dokyoung12345ORCID

Affiliation:

1. Department of Biomedical Science

2. Graduate School

3. Kyung Hee University

4. Seoul 02447

5. Republic of Korea

6. Department of Chemistry

7. College of Natural Science

8. Seoul National University

9. Seoul 08826

10. Laboratory of Vitamin C and Antioxidant Immunology

11. Department of Anatomy and Cell Biology

12. College of Medicine

13. Seoul 03080

14. Department of Anatomy and Neurobiology

15. Korea University

16. Seoul 02841

17. KU Leuven

18. Rega Institute of Medical Research

19. Medicinal Chemistry

20. 3000 Leuven

21. Belgium

Abstract

A fluorophore–protein complex for the visualization of mitochondria and the mouse intestine was developed. The complex formation of a naphthalene-based dipolar dye and serum albumin was identified and its imaging applications were investigated.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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