Subcellular targeting strategies for drug design and delivery
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd2897.pdf
Reference172 articles.
1. Gershell, L. J. & Atkins, J. H. A brief history of novel drug discovery technologies. Nature Rev. Drug Discov. 2, 321–327 (2003). This article gives an excellent timeline on the development of various technologies in drug discovery.
2. Langer, R. Drug delivery. Drugs on target. Science 293, 58–59 (2001). A well written primer on the need for targeted drug delivery to reduce adverse effects.
3. Lipinski, C. A., Lombardo, F., Dominy, B. W. & Feeney, P. J. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. 46, 3–26 (2001). An excellent reference for determining the bioavailability of drugs.
4. Rosen, H. & Abribat, T. The rise and rise of drug delivery. Nature Rev. Drug Discov. 4, 381–385 (2005).
5. Blobel, G. Protein targeting (Nobel lecture). Chembiochem 1, 86–102 (2000).
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