Radical 1,2,3-tricarbofunctionalization of α-vinyl-β-ketoesters enabled by a carbon shift from an all-carbon quaternary center-Reference-Cited by-同舟云学术

Radical 1,2,3-tricarbofunctionalization of α-vinyl-β-ketoesters enabled by a carbon shift from an all-carbon quaternary center

Published:2022 Issue:23 Volume:13 Page:6836-6841
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Zhang Qi¹,Chiou Mong-Feng¹,Ye Changqing¹,Yuan Xiaobin¹,Li Yajun¹²,Bao Hongli¹³^ORCID

Affiliation:

1. Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, State Key Laboratory of Structural Chemistry, Center for Excellence in Molecular Synthesis, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, 155 Yangqiao Road West, Fuzhou, Fujian 350002, P. R. China

2. Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Lingling Road 345, Shanghai 200032, P. R. China

3. University of Chinese Academy of Sciences, Beijing 100049, P. R. China

Abstract

Herein, we report an intermolecular, radical 1,2,3-tricarbofunctionalization of α-vinyl-β-ketoesters to achieve the goal of building molecular complexity via the one-pot multifunctionalization of alkenes.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D2SC00902A

Reference64 articles.

1. Mechanistic approaches to palladium-catalyzed alkene difunctionalization reactions