Attachment of hybridizable oligonucleotides to a silica support and its application for selective extraction of unmodified and antisense oligonucleotides from serum samples-Reference-Cited by-同舟云学术

Attachment of hybridizable oligonucleotides to a silica support and its application for selective extraction of unmodified and antisense oligonucleotides from serum samples

Published:2020 Issue:28 Volume:10 Page:16221-16230
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Studzińska Sylwia¹²³⁴⁵^ORCID,Skoczylas Magdalena¹²³⁴⁵,Bocian Szymon¹²³⁴⁵^ORCID,Dembska Anna⁶²⁷⁸⁵,Buszewski Bogusław¹²³⁴⁵

Affiliation:

1. Chair of Environmental Chemistry and Bioanalytics

2. Faculty of Chemistry

3. Nicolaus Copernicus University in Toruń

4. 87-100 Toruń

5. Poland

6. Laboratory of Bioanalytical Chemistry

7. Adam Mickiewicz University in Poznań

8. 61-614 Poznań

Abstract

The main aim of the present study was the synthesis of an oligonucleotide-based material with high chemical stability, repeatability and specificity to complementary oligonucleotides.

Funder

Narodowe Centrum Nauki

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA01620A

Reference19 articles.

1. Therapeutic Oligonucleotides: State of the Art

2. The Synthesis of Polynucleotide-Celluloses and Their Use in the Fractionation of Polynucleotides

3. Nanostructures in Biodiagnostics

4. Application of Locked Nucleic Acid Oligonucleotides for siRNA Preclinical Bioanalytics

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