Inhibition of Ca<sup>2+</sup>-calpain signaling is a new mechanism using <i>Laminaria japonica</i> polysaccharide to prevent macrophage foam cell formation and atherosclerosis-Reference-Cited by-同舟云学术

Inhibition of Ca²⁺-calpain signaling is a new mechanism using Laminaria japonica polysaccharide to prevent macrophage foam cell formation and atherosclerosis

Published:2023 Issue:9 Volume:14 Page:4036-4048
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Li Xue-Ying¹²,Kuang Dan-Dan¹²,Guo An-Jun¹²,Deng Yuan-Yuan³⁴⁵,Pan Li-Hua¹²,Li Qiang-Ming¹²,Luo Jian-Ping¹²^ORCID,Zha Xue-Qiang¹²⁶^ORCID

Affiliation:

1. Engineering Research Centre of Bioprocess of Ministry of Education, Hefei University of Technology, No. 193 Tunxi Road, Hefei 230009, People's Republic of China

2. School of Food and Biological Engineering, Hefei University of Technology, No. 193 Tunxi Road, Hefei 230009, People's Republic of China

3. Sericultural & Agri-Food Research Institute Guangdong Academy of Agricultural Sciences, Guangzhou 510610, People's Republic of China

4. Key Laboratory of Functional Foods, Ministry of Agriculture and Rural Affairs, Guangzhou 510610, People's Republic of China

5. Guangdong Key Laboratory of Agricultural Products Processing, Guangzhou 510610, People's Republic of China

6. Key Laboratory of Metabolism and Regulation for Major Disease of Anhui Higher Education Institutes, Hefei University of Technology, No. 193 Tunxi Road, Hefei 230009, People's Republic of China

Abstract

The LJP61A suppressed macrophage foam cell formation and atherosclerotic progression by modulating Ca2+-calpain mediated autophagy inhibition.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D2FO04099A

Reference52 articles.