Improving design features and air bubble manipulation techniques for a single-step sandwich electrochemical ELISA incorporating commercial electrodes into capillary-flow driven immunoassay devices-Reference-Cited by-同舟云学术

Improving design features and air bubble manipulation techniques for a single-step sandwich electrochemical ELISA incorporating commercial electrodes into capillary-flow driven immunoassay devices

Published:2024 Issue:7 Volume:149 Page:2034-2044
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Kaewarsa Phuritat¹^ORCID,Schenkel Melissa S.²,Rahn Kira L.²,Laiwattanapaisal Wanida³^ORCID,Henry Charles S.²⁴^ORCID

Affiliation:

1. Graduate Program in Clinical Biochemistry and Molecular Medicine, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand

2. Department of Chemistry, Colorado State, University, Fort Collins, Colorado, 80526, USA

3. Biosensors and Bioanalytical Technology for Cell and Innovative Testing Research Unit, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand

4. Materials and Metallurgy Research Institute, Chulalongkorn University, Bangkok, 10330, Thailand

Abstract

The iceCaDI, a capillary-driven immunoassay device, uses a commercial electrode for single-step electrochemical ELISA. It has a hinge-based assembly, air baffle for reagent dispersal, and vent holes for bubble release, quantifying CRP in 8 min.

Funder

National Research Council of Thailand

Colorado State University

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/AN/D3AN01704D

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